Although he was in ______ trouble, the great man would never

Although he was in ______ trouble, the great man would never lose ____ heart

A./ ; /B./ ; hisC.the; /D.the; his

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A解析考查冠词。英语中一些习惯短语中往往不要冠词。In trouble在困难中；lose heart丧失信心。故选A。